Gene Expression Following TBI

Epigenetics and gene expression are cutting edge concepts which are making their way into the realm of traumatic brain injury. A study (Staffa, K et al. 2012) looked at twelve cases of severe brain injury resulting in death and analyzed whether or not the brain tissue had gene expression different than controls without TBI. They found that several substances were expressed in the cerebellum indicating that the cerebellum is an important target to study further regarding gene expression after TBI. This means that adverse changes in a parent with TBI can be passed to children.